Exploration and Discovery of the COVID-19 Literature through Semantic Visualization (preprint)

We are developing semantic visualization techniques in order to enhance exploration and enable discovery over large datasets of complex networks of relations. Semantic visualization is a method of enabling exploration and discovery over large datasets of complex networks by exploiting the semantics of the relations in them. This involves (i) NLP to extract named entities, relations and knowledge graphs from the original data; (ii) indexing the output and creating representations for all relevant entities and relations that can be visualized in many different ways, e.g., as tag clouds, heat maps, graphs, etc.; (iii) applying parameter reduction operations to the extracted relations, creating "relation containers", or functional entities that can also be visualized using the same methods, allowing the visualization of multiple relations, partial pathways, and exploration across multiple dimensions. Our hope is that this will enable the discovery of novel inferences over relations in complex data that otherwise would go unnoticed. We have applied this to analysis of the recently released CORD-19 dataset.

COVID-19 Literature Knowledge Graph Construction and Drug Repurposing Report Generation (preprint)

To combat COVID-19, both clinicians and scientists need to digest vast amounts of relevant biomedical knowledge in scientific literature to understand the disease mechanism and related biological functions. We have developed a novel and comprehensive knowledge discovery framework, COVID-KG to extract fine-grained multimedia knowledge elements (entities and their visual chemical structures, relations, and events) from scientific literature. We then exploit the constructed multimedia knowledge graphs (KGs) for question answering and report generation, using drug repurposing as a case study. Our framework also provides detailed contextual sentences, subfigures, and knowledge subgraphs as evidence.